E2Q79WX3
type: UserItem
resource: Fascia iliaca block in the emergency department for hip fracture: a randomized, controlled, double-blind trial
tagged: UserTag
  label: *Emergency Service, Hospital
tagged: UserTag
  label: Aged
tagged: UserTag
  label: Aged, 80 and over
tagged: UserTag
  label: Analgesia
tagged: UserTag
  label: Analgesia/methods
tagged: UserTag
  label: Autonomic Nerve Block/*methods
tagged: UserTag
  label: Double-Blind Method
tagged: UserTag
  label: Female
tagged: UserTag
  label: Hip Fractures/*diagnosis/*drug therapy
tagged: UserTag
  label: Hip fractures
tagged: UserTag
  label: Humans
tagged: UserTag
  label: Longitudinal Studies
tagged: UserTag
  label: Lumbosacral plexus
tagged: UserTag
  label: Male
tagged: UserTag
  label: Pain Management/*methods
tagged: UserTag
  label: Pain Measurement/drug effects/*methods
tagged: UserTag
  label: Research (SACAR), Lausanne, Switzerland (50,000 CHF
tagged: UserTag
  label: Retrospective Studies
tagged: UserTag
  label: and from B. Braun (Melsungen AG) to support his clinical research. EA has also
tagged: UserTag
  label: by the other authors.
tagged: UserTag
  label: no grant numbers attributed)
tagged: UserTag
  label: received an honorarium from B. Braun Medical (Melsungen AG). No interest declared

Fascia iliaca block in the emergency department for hip fracture: a randomized, controlled, double-blind trial
type: AcademicArticle
abstract: BACKGROUND: Hip fracture causes moderate to severe pain and while fascia iliaca block has been reported to provide analgesic benefit, most previous trials were unblinded, with subsequent high risks of performance, selection and detection biases. In this randomized, control double-blind trial, we tested the hypothesis that a fascia iliaca block provides effective analgesia for patients suffering from hip fracture. METHODS: Thirty ASA I-III hip fracture patients over 70 years old, who received prehospital morphine, were randomized to receive either a fascia iliaca block using 30 ml of bupivacaine 0.5% with epinephrine 1:200,000 or a sham injection with normal saline. The fascia iliaca block was administered by emergency medicine physicians trained to perform an anatomic landmark-based technique. The primary outcome was the comparison between groups of the longitudinal pain score profiles at rest over the first 45 min following the procedure (numeric rating scale, 0-10). Secondary outcomes included the longitudinal pain score profiles on movement and the comparison over 4 h, 8 h, 12 h, and 24 h after the procedure, along with cumulative intravenous morphine consumption at 24 h. RESULTS: At baseline, the fascia iliaca group had a lower mean pain score than the sham injection group, both at rest (difference = - 0.9, 95%CI [- 2.4, 0.5]) and on movement (difference = - 0.9, 95%CI [- 2.7; 0.9]). These differences remained 45 min after the procedure and the two longitudinal pain score profiles were parallel both for patients at rest and on movement (test of parallelism for patients at rest p = 0.53 and on movement p = 0.45). The same parallel change in pain scores over time was observed over 24 h of follow-up (test of parallelism for patients at rest p = 0.82 and on movement p = 0.12). These results were confirmed after adjustment for gender, ASA score, and cumulative sums of intravenous morphine received pre-procedure and during-follow-up. In addition, there was no differen…
pages: 180
doi: 10.1186/s12877-019-1193-0
source: 31262265
creator: Person
author list: Person
is part of: Issue
  date: 2019-07-03
  volume: 19
  issue: 1
  is part of: BMC Geriatr
    type: Journal
    issn: 1471-2318 (Electronic) 1471-2318 (Linking)

Person
given name: M.
surname: Pasquier

Person
given name: P.
surname: Taffe

Person
given name: O.
surname: Hugli

Person
given name: O.
surname: Borens

Person
given name: K. R.
surname: Kirkham

Person
given name: E.
surname: Albrecht